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PGx Testing
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Published 02/02/2026
If you’re deciding between escitalopram and citalopram, you’re not alone. These are two of the most commonly prescribed SSRIs (selective serotonin reuptake inhibitors) in the UK, particularly for anxiety and depression. They’re closely related medications, and they’re often discussed as if they’re almost interchangeable. In fact, both are influenced by a key drug-metabolising enzyme pathway called CYP2C19, which helps your body process and clear certain SSRIs.
Published 06/01/2026
If you are taking more than one medication, for example something for mental health, something for pain, and something for your stomach or heart, you are not alone. This is incredibly common, especially as we get older or manage more than one condition. The medical term for this is polypharmacy, which simply means taking multiple medications at the same time. Polypharmacy usually refers to taking five or more medications, but even with just two medications, interactions can occur. The risk increases as more drugs are added.
Published 03/11/2025
Many adults with ADHD take more than one medication. One of the most common combinations is an ADHD medicine taken together with an SSRI antidepressant. This may look complicated from the outside, but it is extremely common. Anxiety, low mood and emotional strain often develop during the years when ADHD is present but not yet recognised. Because of this, SSRIs such as sertraline, fluoxetine or citalopram are often started before ADHD medication is introduced.
Published 25/09/2025
If you’re taking a statin like simvastatin, atorvastatin, or rosuvastatin and it’s not working as expected, you’re not alone. You might even be dealing with side effects like muscle aches, tiredness, or poor sleep. It’s frustrating — especially if your doctor increases your dose and nothing improves.
If you’ve tried different medications without success, or experienced side effects that stop you from feeling better, you may have wondered: “Why isn’t my treatment working for me?” Pharmacogenetic testing (PGx) can help. By looking at your DNA, it shows how your body processes medications—giving doctors clues about which drugs may work best, and which may cause problems. But one big question remains: how can I get pharmacogenetic testing on the NHS?
Published 10/09/2025
Pharmacogenetic testing—often shortened to PGx testing—is a type of DNA test that shows how your body processes medicines. Instead of relying on trial and error, PGx can help your doctor choose the right medication and dose from the start. Whether you’re considering antidepressants, pain medication, or heart drugs, PGx testing at home in the UK makes personalised prescribing more accessible than ever.
Pharmacogenetic testing—also known as PGx testing—can reveal why some medicines work well for one person but not for another. If you’ve ever wondered why antidepressants, painkillers, or heart medicines affect people so differently, PGx offers the answer.
Pharmacogenetic testing—often called PGx testing—is quick, simple, and painless. Many patients in the UK are now exploring DNA cheek swab tests for medicines, including antidepressants, ADHD treatments, painkillers, and heart medications. If you’ve wondered what actually happens when you order a test, here’s what to expect.
Pharmacogenetic testing—also known as PGx testing—is completely safe and designed only to help your doctor personalise your medication. Many patients worry about privacy or whether a DNA test reveals more than they’d like. In reality, PGx testing looks only at genes that affect how you process medicines, and in the UK, results are protected under strict data privacy laws like GDPR.
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