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Cardiovascular PGx

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Understanding the best treatment options for cardiovascular conditions can be complex, as individual genetic differences significantly influence how patients respond to medications, and some medicines like Clopidogrel depend on specific genetic pathways to be converted to the active compound. Pharmacogenetic (PGx) testing analyses your genetic profile to provide insights for personalised medication recommendations.

  • 120 genetic markers and key cardiovascular medications covered
  • Produced in the UK
  • Tested in a UK laboratory
  • Easy-to-use, self swab kit
£299 £269.10
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How PGx Testing Can Benefit You

PGx testing offers personalised insights to optimise your cardiovascular treatment, helping you find the right medications faster.

Personalised Prescriptions:

Personalised Prescriptions:

Get medication recommendations tailored to your unique genetic profile, reducing trial and error with treatments.

Reduced Side Effects:

Reduced Side Effects:

Understand how your body may respond to specific cardiovascular medications, helping to avoid unwanted side effects.

Improved Effectiveness:

Improved Effectiveness:

Receive medications more likely to work for you, enhancing your cardiovascular health and wellbeing.

Peace of Mind:

Peace of Mind:

Our testing provides clarity and confidence in your treatment decisions, helping you manage heart disease, hypertension, arrhythmias, and more.

Save Money:

Save Money:

PGx testing reduces the need for trial-and-error prescriptions, saving you money and time on ineffective treatments and unnecessary doctor visits.

What Our Pharmacogenomics Report Includes

Our PGx report is designed to give you clear, actionable insights into how your body may respond to different medications. You're report includes:

  1. Example Report

    Medication Summary

    A quick reference guide listing medications relevant to your condition, categorised and numbered by the magnitude of the gene- drug interaction.

  2. Example Report

    Medication Summary Table

    This section provides a more detailed overview of the medications relevant to certain medical conditions. Each drug is categorised as follows:

    - Mild or no known gene-drug interaction (use as recommended)
    - Moderate gene-drug interaction (adjust based on your genetic profile and conditions to achieve optimum therapeutic outcome or avoid adverse reactions)
    - Severe gene-drug interaction (review based on likely adverse drug reaction risk and choose alternative medication)

  3. Example Report

    Medication Report

    A detailed breakdown of each medication, including your phenotype, gene-drug interactions, and what these mean for your treatment.

How Pharmacogenomic Testing Works

Pharmacogenomics (PGx) testing is a straightforward procedure involving an at-home buccal swab or dried blood spot (finger prick blood) collection or healthcare professional led sample collection, followed by laboratory testing and results delivery. Here’s an overview of the key steps involved in PGx testing:

Step 1

Sample Collection

Collecting your sample is easy and straightforward! We use a gentle cheek (buccal) swab which will be sent to you in the post. Collecting DNA from your saliva is the first step in unlocking your response to different medications.

Sample Collection

Step 2

Genetic Analysis

Your sample is carefully analysed in our advanced laboratory to uncover genetic insights that may affect how your body processes medications. At AutoDiagnostics, we use top-of-the-line technology, including ThermoFisher and Illumina Platforms to analyse genetic markers related to drug absorption, distribution, metabolism and excretion. Understanding your genetic variations gives us valuable insights into how you uniquely respond to various medications.

Genetic Analysis

Step 3

Comprehensive Report

Your report will include a comprehensive look at drug-gene interactions as well as a guide on how to dose (reduce or increase) certain medications. In cases where strong drug-gene interactions exist, the report will help your healthcare provider select the right medication to minimise the risk of adverse drug reactions or treatment failure. If you don’t have a healthcare provider, we have a number of trusted experts you can turn to.

Comprehensive Report

Cardiovascular Pharmacogenomics Testing Panel

Our genetic testing panels are designed to help you find the right medications for cardiovascular conditions like hypertension, coronary artery disease, heart failure, arrhythmias, hyperlipidemia, and more. By analysing your unique genetic profile, we can provide insights into how your body may respond to various medications, including statins, blood thinners, beta-blockers, ACE inhibitors, and more.

Take control of your cardiovascular health with a personalised approach that’s tailored just for you.

Antiarrhythmics

DigoxinFlecainideQuinidinePropafenone

Antithrombotics

AcenocoumarolClopidogrelPhenprocoumonPrasugrelTicagrelorWarfarin

Beta Blockers

CarvedilolMetoprololNebivololPropranolol

When and Why is an AttoPGx Test Appropriate for Cardiovascular Health?

The AttoPGx Cardiovascular test is a relevant tool for people who meet one or more of the following criteria:

  • Are taking or considering medications for cardiovascular conditions like hypertension, coronary artery disease, arrhythmias, or heart failure.
  • Feel that their current treatment is ineffective.
  • Experience side effects from their current cardiovascular medication.
  • Are hesitant to start treatment due to concerns about side effects or ineffectiveness.

By taking the test, you provide your healthcare professional with an essential tool to ensure that your prescriptions are tailored to your unique genetics. As a result, your treatment plan can be more effective and efficient.

Important

IMPORTANT: DO NOT MAKE ANY CHANGES TO YOUR CURRENT MEDICATION(S) WITHOUT CONSULTING YOUR HEALTHCARE PROVIDER FIRST.

While your genetics is important, other factors also contribute to how you respond to medications. The final choice of medication used will be based on your healthcare provider’s professional judgement and may be different to what is recommended in this report. The AttoPGx test does not determine your risk of any health problem or condition. It only evaluates select portions of your DNA that help predict how you may respond to the medications covered.

FAQs

What is PGx testing for cardiovascular health?

Pharmacogenomic (PGx) testing analyses your DNA to understand how your body responds to medications used for cardiovascular conditions, such as hypertension, heart disease, and arrhythmias. It helps healthcare professionals to tailor treatments to your genetic profile, ensuring medications are effective and minimising side effects.

Who can benefit from PGx testing?

This test is particularly helpful for individuals who:

  • Are taking or considering medications for cardiovascular conditions
  • Feel their current treatment is ineffective
  • Experience side effects from medications
  • Are hesitant to start treatment due to concerns about side effects or ineffectiveness

What medications are covered in the test?

The test includes insights into key cardiovascular medications such as statins, beta-blockers, ACE inhibitors, blood thinners, and more.

How does the test work?

  1. Sample Collection: A cheek swab is provided in a simple at-home kit.
  2. Genetic Analysis: Your sample is analysed in our UK laboratory using cutting-edge technology to assess over 120 genetic markers relevant to response to medications.
  3. Comprehensive Report: You receive a detailed report with personalised medication recommendations and dosage adjustments, shared with your healthcare provider.

Where is the test performed?

The test is processed in a UK laboratory using advanced platforms including ThermoFisher OpenArray technology and/or Illumina iScan system, ensuring precise results.

Is the test painful?

No, the test is completely non-invasive. It involves a simple cheek swab that you can complete at home in just a few minutes.

How accurate is PGx testing?

Our testing process uses state-of-the-art technology and analyses over 120 genetic markers to provide precise, clinically actionable insights. However, genetics is just one factor influencing medication response, and results should be used in consultation with a healthcare provider.

Do I need a doctor to interpret my PGx results?

While the report is designed to be user-friendly, we strongly recommend discussing your results with your healthcare provider. They can interpret the findings in the context of your overall health and treatment plan.

How does PGx testing help reduce side effects?

By analysing your genetic profile, PGx testing identifies medications that are more likely to work for you and those that might cause adverse reactions. This helps your healthcare provider to make more informed decisions, minimising the risk of side effects.

What happens if my genetic profile suggests my current medication isn’t suitable?

Your healthcare provider may use the report to adjust your treatment plan, such as changing the medication or dosage, to find a more effective and safer option.

Can I change my medications based on the report?

No. You should never adjust your medications without consulting your healthcare provider. The PGx test provides guidance for your healthcare practitioner, who will make the final treatment decisions.