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Mental Health & ADHD PGx

(5 Reviews)

Understanding the best treatment options for mental health can be challenging due to the genetic differences between individuals and their impact on responses to medications.

Pharmacogenetic (PGx) testing analyses your genetic profile to provide insights for personalised medication recommendations.

120 genetic markers and key mental health medications covered
Produced in the UK
Tested in a UK laboratory
Easy-to-use, self swab kit

£299 £269.10

How PGx Testing Can Benefit You

PGx testing offers personalised insights to optimise your mental health treatment, helping you find the right medications faster.

Personalised Prescriptions:

Get recommendations suited to your unique genetic makeup, minimising trial and error with medications

Reduced Side Effects:

Understand how your body may respond to specific medications, helping to avoid unwanted side effects

Improved Effectiveness:

Receive medications more likely to work for you, improving your mental health journey

Peace of Mind:

Our testing provides clarity and confidence in your mental health care choices

Save Money:

PGx testing reduces the need for trial-and-error prescriptions, saving you money and time on ineffective treatments and unnecessary doctor visits.

What Our Pharmacogenomics Report Includes

Our PGx report is designed to give you clear, actionable insights into how your body may respond to different medications. You're report includes:

Medication Summary

A quick reference guide listing medications relevant to your condition, categorised and numbered by the magnitude of the gene- drug interaction.
Medication Summary Table

This section provides a more detailed overview of the medications relevant to certain medical conditions. Each drug is categorised as follows:

- Mild or no known gene-drug interaction (use as recommended)
- Moderate gene-drug interaction (adjust based on your genetic profile and conditions to achieve optimum therapeutic outcome or avoid adverse reactions)
- Severe gene-drug interaction (review based on likely adverse drug reaction risk and choose alternative medication)
Medication Report

A detailed breakdown of each medication, including your phenotype, gene-drug interactions, and what these mean for your treatment.

How Pharmacogenomic Testing Works

Pharmacogenomics (PGx) testing is a straightforward procedure involving an at-home buccal swab or dried blood spot (finger prick blood) collection or healthcare professional led sample collection, followed by laboratory testing and results delivery. Here’s an overview of the key steps involved in PGx testing:

Step 1

Sample Collection

Collecting your sample is easy and straightforward! We use a gentle cheek (buccal) swab which will be sent to you in the post. Collecting DNA from your saliva is the first step in unlocking your response to different medications.

Step 2

Genetic Analysis

Your sample is carefully analysed in our advanced laboratory to uncover genetic insights that may affect how your body processes medications. At AutoDiagnostics, we use top-of-the-line technology, including ThermoFisher and Illumina Platforms to analyse genetic markers related to drug absorption, distribution, metabolism and excretion. Understanding your genetic variations gives us valuable insights into how you uniquely respond to various medications.

Step 3

Comprehensive Report

Your report will include a comprehensive look at drug-gene interactions as well as a guide on how to dose (reduce or increase) certain medications. In cases where strong drug-gene interactions exist, the report will help your healthcare provider select the right medication to minimise the risk of adverse drug reactions or treatment failure. If you don’t have a healthcare provider, we have a number of trusted experts you can turn to.

Pharmacogenomics Testing Panel

Our genetic testing panels are designed to help you find the right medications for mental health conditions like depression, anxiety, post-traumatic stress disorder, adjustment disorder, bipolar disorder, schizophrenia, obsessive-compulsive disorder, and attention deficit disorder with or without hyperactivity (ADHD). By analysing your unique genetic profile, we can provide insights into how your body may respond to various medications, including antidepressants, antipsychotics, anti-anxiety medications, stimulants, and more.

Take control of your mental health care journey with a personalised approach that’s tailored just for you.

Antidepressants

Selective Serotonin Reuptake Inhibitors (SSRIs)

CitalopramEscitalopramFluoxetineFluvoxamineParoxetineSertralineVortioxetine

Tricyclic Antidepressants (TCAs)

AmitriptylineAmoxapineClomipramineDesipramineDoxepinImipramineNortriptylineProtriptylineTrimipramine

Monoamine Oxidase Inhibitors (MAOIs)

Moclobemide

Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)

AtomoxetineDesvenlafaxineDuloxetineVenlafaxine

Antipsychotics

AripiprazoleAripiprazole lauroxilBrexpiprazoleClozapineHaloperidolIloperidoneLurasidoneOlanzapinePimozideQuetiapineRisperidoneThioridazineZuclopenthixol

When and Why is an AttoPGx Test Appropriate for Mental Health?

The AttoPGx Mental Health test (Psychiatry and ADHD) is a relevant tool for people who meet one or more of the following criteria:

Are taking medication(s) to treat mental health disorders and/or ADHD
Feel that their current medication is ineffective
Experiencing side effects from taking medication
Are reluctant to start treatment for fear of side effects or the perception that it won't be effective.

By taking the test, you provide your healthcare professional with an essential tool to ensure that your prescriptions are tailored to your unique genetics. As a result, your road to recovery can be shorter and more effective.

IMPORTANT: DO NOT MAKE ANY CHANGES TO YOUR CURRENT MEDICATION(S) WITHOUT CONSULTING YOUR HEALTHCARE PROVIDER FIRST.

While your genetics is important, other factors also contribute to how you respond to medications. The final choice of medication used will be based on your healthcare provider’s professional judgement and may be different to what is recommended in this report. The AttoPGx test does not determine your risk of any health problem or condition. It only evaluates select portions of your DNA that help predict how you may respond to the medications covered.

FAQs

What is PGx testing for mental health?

Pharmacogenomic (PGx) testing analyses your DNA to understand how your body responds to certain medications. It helps healthcare professionals to tailor treatments to your unique genetic profile, ensuring medications are effective and minimising side effects.

Who can benefit from PGx testing?

This test is particularly helpful for individuals who:

Are taking medications for mental health disorders or ADHD.
Feel their current medication is ineffective.
Experience side effects from medications.
Are hesitant to start treatment due to concerns about side effects or ineffectiveness.

What medications are covered in the test?

The test includes insights into over 37 key mental health medications coveringsuch antidepressants, antipsychotics, anti-anxiety medications, stimulants, and more.

How does the test work?

Sample Collection: A cheek swab is provided in a simple at-home kit.
Genetic Analysis: Your sample is analysed in our UK laboratory using cutting-edge technology to assess over 120 genetic markers relevant to response to medications.
Comprehensive Report: You receive a detailed report with personalised medication recommendations and dosage adjustments, shared with your healthcare provider.

Where is the test performed?

The test is processed in a UK laboratory using advanced platforms including ThermoFisher OpenArray technology and/or Illumina iScan system, ensuring precise results.

Is the test painful?

No, the test is completely non-invasive. It involves a simple cheek swab that you can complete at home in just a few minutes.

How accurate is PGx testing?

Our testing process uses state-of-the-art technology and analyses over 120 genetic markers to provide precise, clinically actionable insights. However, genetics is just one factor influencing medication response, and results should be used in consultation with a healthcare provider.

Do I need a doctor to interpret my PGx results?

While the report is designed to be user-friendly, we strongly recommend discussing your results with your healthcare provider. They can interpret the findings in the context of your overall health and treatment plan.

How does PGx testing help reduce side effects?

By analysing your genetic profile, PGx testing identifies medications that are more likely to work for you and those that might cause adverse reactions. This helps your healthcare provider to make more informed decisions, minimising the risk of side effects.

What happens if my genetic profile suggests my current medication isn’t suitable?

Your healthcare provider may use the report to adjust your treatment plan, such as changing the medication or dosage, to find a more effective and safer option.

Can I change my medications based on the report?

No. You should never adjust your medications without consulting your healthcare provider. The PGx test provides guidance for your healthcare practitioner, who will make the final treatment decisions.