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PGx Testing

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Pain Management PGx

(5 Reviews)

Managing pain effectively can be challenging, as individuals respond differently to medications due to genetic differences.

Pharmacogenetic (PGx) testing analyses your genetic profile to provide insights for personalised medication recommendations.

120 genetic markers and key pain management medications covered
Produced in the UK
Tested in a UK laboratory
Easy-to-use, self swab kit

£299 £269.10

How PGx Testing Can Benefit You

PGx testing offers personalised insights to optimise your pain management treatment, helping you find the right medications faster.

Personalised Prescriptions:

Get medication recommendations tailored to your unique genetic profile, reducing trial and error with pain treatments.

Reduced Side Effects:

Understand how your body may respond to specific pain medications, helping to avoid unwanted side effects.

Improved Effectiveness:

Receive pain relief medications that are more likely to work for you, enhancing your quality of life.

Peace of Mind:

Our testing provides clarity and confidence in your pain management decisions, making your treatment more predictable and effective.

Save Money:

PGx testing reduces the need for trial-and-error prescriptions, saving you money and time on ineffective treatments and unnecessary doctor visits.

What Our Pharmacogenomics Report Includes

Our PGx report is designed to give you clear, actionable insights into how your body may respond to different medications. You're report includes:

Medication Summary

A quick reference guide listing medications relevant to your condition, categorised and numbered by the magnitude of the gene- drug interaction.
Medication Summary Table

This section provides a more detailed overview of the medications relevant to certain medical conditions. Each drug is categorised as follows:

- Mild or no known gene-drug interaction (use as recommended)
- Moderate gene-drug interaction (adjust based on your genetic profile and conditions to achieve optimum therapeutic outcome or avoid adverse reactions)
- Severe gene-drug interaction (review based on likely adverse drug reaction risk and choose alternative medication)
Medication Report

A detailed breakdown of each medication, including your phenotype, gene-drug interactions, and what these mean for your treatment.

How Pharmacogenomic Testing Works

Pharmacogenomics (PGx) testing is a straightforward procedure involving an at-home buccal swab or dried blood spot (finger prick blood) collection or healthcare professional led sample collection, followed by laboratory testing and results delivery. Here’s an overview of the key steps involved in PGx testing:

Step 1

Sample Collection

Collecting your sample is easy and straightforward! We use a gentle cheek (buccal) swab which will be sent to you in the post. Collecting DNA from your saliva is the first step in unlocking your response to different medications.

Step 2

Genetic Analysis

Your sample is carefully analysed in our advanced laboratory to uncover genetic insights that may affect how your body processes medications. At AutoDiagnostics, we use top-of-the-line technology, including ThermoFisher and Illumina Platforms to analyse genetic markers related to drug absorption, distribution, metabolism and excretion. Understanding your genetic variations gives us valuable insights into how you uniquely respond to various medications.

Step 3

Comprehensive Report

Your report will include a comprehensive look at drug-gene interactions as well as a guide on how to dose (reduce or increase) certain medications. In cases where strong drug-gene interactions exist, the report will help your healthcare provider select the right medication to minimise the risk of adverse drug reactions or treatment failure. If you don’t have a healthcare provider, we have a number of trusted experts you can turn to.

When and Why is an AttoPGx Test Appropriate for Pain Management?

The AttoPGx Pain Management test is a relevant tool for people who meet one or more of the following criteria:

Are taking or considering medications for chronic pain, migraines, or other pain conditions.
Feel that their current pain management treatment is ineffective.
Experience side effects from their current pain medications.
Are concerned about the risk of addiction or adverse reactions to opioid-based painkillers.

By taking the test, you provide your healthcare professional with an essential tool to ensure that your prescriptions are tailored to your unique genetics. As a result, your pain management plan can be more effective and safer.

IMPORTANT: DO NOT MAKE ANY CHANGES TO YOUR CURRENT MEDICATION(S) WITHOUT CONSULTING YOUR HEALTHCARE PROVIDER FIRST.

While your genetics is important, other factors also contribute to how you respond to medications. The final choice of medication used will be based on your healthcare provider’s professional judgement and may be different to what is recommended in this report. The AttoPGx test does not determine your risk of any health problem or condition. It only evaluates select portions of your DNA that help predict how you may respond to the medications covered.

FAQs

What is PGx testing for pain management?

Pharmacogenomic (PGx) testing analyses your DNA to understand how your body responds to pain medications, such as opioids, NSAIDs, and anticonvulsants. It helps healthcare professionals tailor treatments to your genetic profile, ensuring medications are effective and minimizing side effects.

Who can benefit from PGx testing?

This test is particularly helpful for individuals who:

Are taking or considering medications for chronic pain or other pain conditions.
Feel their current treatment is ineffective.
Experience side effects from pain medications.
Are concerned about the risk of addiction or adverse reactions to opioids.

What medications are covered in the test?

The test includes insights into key pain management medications, including opioids, NSAIDs, antidepressants, anticonvulsants, muscle relaxants, and more.

How does the test work?

Sample Collection: A cheek swab is provided in a simple at-home kit.
Genetic Analysis: Your sample is analysed in our UK laboratory using cutting-edge technology to assess over 120 genetic markers relevant to response to medications.
Comprehensive Report: You receive a detailed report with personalised medication recommendations and dosage adjustments, shared with your healthcare provider.

Where is the test performed?

The test is processed in a UK laboratory using advanced platforms including ThermoFisher OpenArray technology and/or Illumina iScan system, ensuring precise results.

Is the test painful?

No, the test is completely non-invasive. It involves a simple cheek swab that you can complete at home in just a few minutes.

How accurate is PGx testing?

Our testing process uses state-of-the-art technology and analyses over 120 genetic markers to provide precise, clinically actionable insights. However, genetics is just one factor influencing medication response, and results should be used in consultation with a healthcare provider.

Do I need a doctor to interpret my PGx results?

While the report is designed to be user-friendly, we strongly recommend discussing your results with your healthcare provider. They can interpret the findings in the context of your overall health and treatment plan.

How does PGx testing help reduce side effects?

By analysing your genetic profile, PGx testing identifies medications that are more likely to work for you and those that might cause adverse reactions. This helps your healthcare provider to make more informed decisions, minimising the risk of side effects.

What happens if my genetic profile suggests my current medication isn’t suitable?

Your healthcare provider may use the report to adjust your treatment plan, such as changing the medication or dosage, to find a more effective and safer option.

Can I change my medications based on the report?

No. You should never adjust your medications without consulting your healthcare provider. The PGx test provides guidance for your healthcare practitioner, who will make the final treatment decisions.